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Glossary entry

English term or phrase:

PYRAZINE GPR40 AGONISTS

Arabic translation:

منهضات جي بي إر 40 بيرازين

Added to glossary by TargamaT team
Jun 11, 2015 17:31
8 yrs ago
English term

PYRAZINE GPR40 AGONISTS

English to Arabic Law/Patents Medical (general) Biomedicine
PYRAZINE GPR40 AGONISTS FOR THE TREATMENT OF TYPE II DIABETES
Proposed translations (Arabic)
4 +1 منهضات جي بي إر 40 بيرازين
5 نَاهِضات أو محاكيات مستقبلات الاقتران ببروتين سي 40 بَيرازين
4 ناهضات جي بي آر 40 بايرازين
4 استخدام تركيبات البيرازين لتحفيز مستقبل GRP40 كعلاج للسكري
References
pyrazine and GPR40 agonists
Change log

Aug 17, 2015 05:28: TargamaT team Created KOG entry

Discussion

liz askew Jun 11, 2015:
I ask this because I am having great difficulty finding bona fide En references to your phrase:)
liz askew Jun 11, 2015:
Just out of interest, do you think the source text is correct?
liz askew Jun 11, 2015:
Useful?
http://www.google.com.ar/patents/WO2006125958A1?cl=en
Fathy Shehatto (asker) Jun 11, 2015:
my own suggestion تنشيط أو تحفيز المستقبلات المقترنة بالبروتين ج التي تنتمي لعائلة البيرازين
Fathy Shehatto (asker) Jun 11, 2015:
UMD link Also the link you provided is just a link to UMD - no results are there
Fathy Shehatto (asker) Jun 11, 2015:
Hello my brother "Targmat" The meaning of the phrase "GPR40 AGONISTS" is very clear. I want to know what is the relation between PYRAZINE and GPR40 AGONISTS. I am sorry to let you know that the Arabic term you provided is not found anywhere.

Proposed translations

+1
7 mins
Selected

منهضات جي بي إر 40 بيرازين

منهضات جي بي إر 40 بيرازين

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Note added at 7 mins (2015-06-11 17:39:51 GMT)
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http://www.emro.who.int/Unified-Medical-Dictionary.html

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Note added at 20 mins (2015-06-11 17:52:12 GMT)
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أخي فتحي البيرازين مادة صيدلانية وتراها منقحرة أيضًا في المعجم الطبي الموحد

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Note added at 21 mins (2015-06-11 17:53:05 GMT)
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نعم عليك تقسيم المصطلح إلى مكوناته
AGONIST
PYRAZINE

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Note added at 1 hr (2015-06-11 18:57:02 GMT)
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Free fatty acid receptor= GPR40

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Note added at 1 hr (2015-06-11 18:57:49 GMT)
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أبقيها جي بي إر 40 وأضع بين قوسين شرحها

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Note added at 13 hrs (2015-06-12 06:55:02 GMT)
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http://en.wikipedia.org/wiki/Free_fatty_acid_receptor_1
Note from asker:
GPR40 is a receptor that belongs to "G protein-coupled receptor", and yes it is a free fatty acid receptor. But again how it is related to PYRAZINE. I need a referenced answer of possible
I mean "GPR40" belongs to the family of GPCRs "G protein-coupled receptors"
Peer comment(s):
agree Liliane Hatem
9 mins
شكرًا جزيلا :-))
Something went wrong...
4 KudoZ points awarded for this answer.
40 mins

ناهضات جي بي آر 40 بايرازين

ناهضات جي بي آر 40 بايرازين
Something went wrong...
6 days

نَاهِضات أو محاكيات مستقبلات الاقتران ببروتين سي 40 بَيرازين

نَاهِضات أو محاكيات مستقبلات الاقتران ببروتين سي 40 بَيرازين
Something went wrong...
30 days

استخدام تركيبات البيرازين لتحفيز مستقبل GRP40 كعلاج للسكري

يتم عمومًا استعمال تركيبات البيرازين لتثبيط أو تحفيز مستقبلات مختلفة كعلاج للعديد من الأمراض والحالات المرضية.
Reference:

https://www.google.co.in/patents/WO2013105061A1?cl=en

Something went wrong...

Reference comments

1 hr
Reference:

pyrazine and GPR40 agonists

would make more sense

https://books.google.co.uk/books?id=BVfDemDiYDoC&pg=PA321&lp...

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Note added at 1 hr (2015-06-11 19:09:39 GMT)
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Full Text - Diabetes Care
care.diabetesjournals.org/content/36/Supplement_2/S175.full
by CF Burant - ‎2013 - ‎Cited by 14 - ‎Related articles
GPR40 agonists have shown efficacy in increasing insulin secretion and lowering blood glucose in rodent models of type 2 diabetes. Recent phase I and phase ...

as I say, I have not found your phrase per se

nor have I found any evidence that Pyrazine is a GPR40 agonist!
Note from asker:
Thanks for this link, Liz
Something went wrong...
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