Glossary entry (derived from question below)
Feb 12, 2010 16:39
14 yrs ago
2 viewers *
Italian term
maturazione
Italian to English
Tech/Engineering
Chemistry; Chem Sci/Eng
Gabapentin rilavorazione
Sommario del procedimento
Dopo raffreddamento e maturazione del cristallo il prodotto viene isolato mediante centrifugazione e lavato con isopropanolo a freddo
Sommario del procedimento
Dopo raffreddamento e maturazione del cristallo il prodotto viene isolato mediante centrifugazione e lavato con isopropanolo a freddo
Proposed translations
(English)
1 +1 | maturation | liz askew |
4 | maturation | Dr Lofthouse |
3 -1 | precipitation | Alexander Cormack (X) |
Change log
Feb 18, 2010 17:09: liz askew Created KOG entry
Proposed translations
+1
20 mins
4 KudoZ points awarded for this answer.
22 mins
maturation
in this context, it is an alternative way of saying 'development of' or 'formation of'
-1
1 hr
precipitation
As the solution cools the crystals precipitate.
The solution obtained is allowed to cool, it being desirable, although not strictly necessary, to seed it with some crystals of pharmaceutical grade anhydrous gabapentin when the temperature of the said solution lies between 30° C and 50° C. In order to complete the precipitation exhaustively, it is preferable to add, when the suspension is at room temperature, an alcoholic solvent of lower gabapentin-dissolving capacity, for example isopropanol.
http://www.freepatentsonline.com/EP1174418.html
The solution obtained is allowed to cool, it being desirable, although not strictly necessary, to seed it with some crystals of pharmaceutical grade anhydrous gabapentin when the temperature of the said solution lies between 30° C and 50° C. In order to complete the precipitation exhaustively, it is preferable to add, when the suspension is at room temperature, an alcoholic solvent of lower gabapentin-dissolving capacity, for example isopropanol.
http://www.freepatentsonline.com/EP1174418.html
Peer comment(s):
disagree |
Gerardo Della Greca
: se no diceva precipitazione - dal testo in esempio non è detto che il cristallo sia in soluzione in questa fase del processo
18 hrs
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è vero che non è detto, ma spiegherebbe perchè il prodotto viene centrifugato, ovvero per separare i cristalli solidi dalla soluzione. tuttavia si potrebbe anche dire "crystallisation", termine anche lui che viene utilzzato in questo contesto.
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